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POTS & Autoimmunity

Research Articles

These articles appear in peer reviewed, scientific journals and are written by those active in researching POTS and other forms of dysautonomia.  When reading journal articles, it can be helpful to focus mainly on the abstract, introduction/background, and discussion section of the paper to get the main idea of the paper.

Is Postural Tachycardia Syndrome an Autoimmune Disorder? And Other Updates on Recent Autonomic Research. 2020.  Read Article

Infectious Mononucleosis Complicated by Peritonsillar Abscess and Postural Orthostatic Tachycardia Syndrome: A case report. 2020. Sage Journals.  Read Article

Human papillomavirus (HPV) vaccine and autonomic disorders: a position statement from the American Autonomic Society. 2020. Autonomic Neuroscience.  Read Article 

A Functional Cell-Based Bioassay for Assessing Adrenergic Autoantibody Activity in Postural Tachycardia Syndrome. 2019. Journal of Translational Autoimmunity.  Read Article 

Hop to It: The First Animal Model of Autoimmune Postural Orthostatic Tachycardia Syndrome. 2019. Journal of the American Heart Association.  Read Article 

Adrenergic Autoantibody‐Induced Postural Tachycardia Syndrome in Rabbits. 2019. Journal of the American Heart Association.  Read Article 

Complex Syndromes of Chronic Pain, Fatigue and Cognitive Impairment Linked to Autoimmune Dysautonomia and Small Fiber Neuropathy. 2020. Clinical Immunology.  Read Article  

Proconvertase Furin Is Downregulated in Postural Orthostatic Tachycardia Syndrome. 2019. Clinical Immunology.  Read Article

A Functional Cell-Based Bioassay for Assessing Adrenergic Autoantibody Activity in Postural Tachycardia Syndrome. 2019. Journal of Translational Autoimmunity.  Read Article

Postural Orthostatic Tachycardia Syndrome in Pediatric Patients with Celiac Disease and Relationship with Tissue Transglutaminase Antibody Levels and HLA Tissue Group. Haydarpasa Numune Medical Journal.  Read Article 

Evaluating and Managing Postural Tachycardia Syndrome. 2019. Cleveland Clinic Journal of Medicine.  Read Article 

Human Leukocyte Antigen Associations in Postural Tachycardia Syndrome. 2019. Annals of Clinical and Translational Neurology.  Read Article 

Postural Orthostatic Tachycardia Syndrome: Clinical Presentation, Aetiology and Management. 2019. Journal of Internal Medicine.  Read Article

Postural Orthostatic Tachycardia Syndrome: JACC Focus Seminar. 2019. Journal of the American College of Cardiology.  Read Article 

Postural Orthostatic Tachycardia Syndrome Is Associated with Elevated G-Protein Coupled Receptor Autoantibodies. 2019. Journal of the American Heart Association.  Read Article 

Increased Prevalence of Autonomic Dysfunction due to Postural Orthostatic Tachycardia Syndrome in Patients with Eosinophilic Gastrointestinal Disorders. 2019. Journal of Gastrointestinal and Liver Diseases.  Read Article 

Autoantibodies against Autonomic Nerve Receptors in Adolescent Japanese Girls after Immunization with Human Papillomavirus Vaccine. 2019. Ann Arthritis Clin Rheumatol.  Read Article 

The Global Rise of Chronic Diseases: Why Broaden the Paradigm to Include Tick-borne Illness and Environmental Toxin Exposure? 2019.  Read Article

Myalgia and chronic fatigue syndrome following immunization: macrophagic myofasciitis and animal studies support linkage to aluminum adjuvant persistency and diffusion in the immune system. 2019. Autoimmunity Reviews.  Read Article 

Autoimmune postural orthostatic tachycardia syndrome. 2018. Annals of Clinical Translational Neurology.  Read Article

Autoimmunity in postural orthostatic tachycardia syndrome: Current Understanding. 2018. Autonomic Neuroscience: Basic and Clinical.  Read Article

Autonomic dysfunction and HPV immunization: an overview. 2018. Immunologic Research.  Read Article

Autoimmunity, Autonomic Neuropathy, and the HPV Vaccination: A Vulnerable Subpopulation. 2018. Clinical Pediatrics.  Read Article

Angiotensin II Type 1 Receptor Autoantibodies in Postural Tachycardia Syndrome. 2018. Journal of the American Heart Association.  Read Article

Reports of Postural Orthostatic Tachycardia Syndrome After Human Papillomavirus Vaccination in the Vaccine Adverse Event Reporting System. 2017. Journal of Adolescent Health.  Read Article

Incidence rates of Guillain Barré (GBS), chronic fatigue/systemic exertion intolerance disease (CFS/SEID) and postural orthostatic tachycardia syndrome (POTS) prior to introduction of human papilloma virus (HPV) vaccination among adolescent girls in Finland. 2017. ELSEVIER. Read Article

Antiadrenergic Autoimmunity in Postural Tachycardia Syndrome. 2016. Europace.  Read Article

Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family. 2016. Lupus.  Read Article

Hypothesis: Human papillomavirus vaccination syndrome—small fiber neuropathy and dysautonomia could be its underlying pathogenesis. 2015. Clinical Rheumatology. Read Article

Autoimmune Basis for Postural Tachycardia Syndrome. 2014. Journal of the American Heart Association.  Read Article

Postural tachycardia syndrome following human papillomavirus vaccination. 2014. European Journal of Neurology.    Read Article

Postural Orthostatic Tachycardia With Chronic Fatigue After HPV Vaccination as Part of the “Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants” Case Report and Literature Review. 2014. Journal of Investigative Medicine.    Read Article

Autoantibody Activation of Beta-Adrenergic and Muscarinic Receptors Contributes to an “Autoimmune” Orthostatic Hypotension. 2013. Journal of the American Society of Hypertension.    Read Article

Autoimmunoreactive IgGs from patients with postural orthostatic tachycardia syndrome. 2012. Proteonomic Clinical Applications.    Read Article

Peripherin-IgG Association with Neurologic and Endocrine Autoimmunity. 2010. Journal of Autoimmunity.    Read Article

Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy. 2010. Autonomic Neurology.    Read Article

Postural Orthostatic Tachycardia Syndrome after Vaccination with Gardisil.  2010. Letter to the Editor. European Journal of Neurology.     Read Article

Other Autonomic Neuropathies Associated with Ganglionic Antibody. 2009. Autonomic Neurology.    Read Article

Autonomic Ganglia: Target and Novel Therapeutic Tool. 2008. Neurology.    Read Article

Autoantibodies to Ganglionic Acetylcholine Receptors in Autoimmune Autonomic Neuropathies. 2000. The New England Journal of Medicine.  Read Article