Skip to main content

POTS in Children & Teens

Research Articles

These articles appear in peer reviewed, scientific journals and are written by those active in researching POTS and other forms of dysautonomia.  When reading journal articles, it can be helpful to focus mainly on the abstract, introduction/background, and discussion section of the paper to get the main idea of the paper.

Screening for Orthostatic Intolerance in Symptomatic Children Presenting for Concussion Care. 2020. Clinical Pediatrics.  Read Article

Demographic and Clinical Features of Pediatric Patients with Orthostatic Intolerance and an Abnormal Head-Up Tilt Table Test: A Retrospective Descriptive Study. 2020. Pediatrics & Neonatology.  Read Article

Diagnostic and prognostic value of T-wave amplitude difference between supine and orthostatic electrocardiogram in children and adolescents with postural orthostatic tachycardia syndrome. 2020.  Annals of Noninvasive Electrocardiology.  Read Article

Pediatric-Onset Postural Orthostatic Tachycardia Syndrome in a Single Tertiary Care Center. 2020. Journal of Child Neurology.  Read Article

Pathophysiology and Individualized Management of Vasovagal Syncope and Postural Tachycardia Syndrome in Children and Adolescents: An Update. 2020. Neuroscience Bulletin.  Read Article

 Update on Pediatric Gastroparesis: A Review of the Published Literature and Recommendations for Future Research. 2020.  Neurogastroenterology & Motility.  Read Article

Arrhythmogenic Right Ventricular Cardiomyopathy in a Pediatric Patient. 2020. JACC: Case Reports.  Read Article

Body mass index is decreased in children and adolescents with postural tachycardia syndrome. 2019.  The Turkish Journal of Pediatrics.  Read Article

Human papillomavirus vaccination and postural tachycardia syndrome, deconditioning and exercise-induced hyperalgesia: An alternate interpretation of the reported adverse reaction. 2020.  Read Article

Postural Orthostatic Tachycardia Syndrome in Pediatric Patients with Celiac Disease and Relationship with Tissue Transglutaminase Antibody Levels and HLA Tissue Group. 2020. Haydarpasa Numune Medical Journal.  Read Article

Long-Term Outcomes of Children and Adolescents With Postural Tachycardia Syndrome After Conventional Treatment. 2019. Frontiers in Pediatrics.  Read Article

Pediatric dysautonomia: Much‐maligned, often overmedicated, but not as complex as you think. 2019.  Read Article

The Benefits of Oral Rehydration on Orthostatic Intolerance in Children with Postural Tachycardia Syndrome. 2019.  The Journal of Pediatrics.  Read Article

Pubertal Hormonal Changes and the Autonomic Nervous System: Potential Role in Pediatric Orthostatic Intolerance. 2019. Frontiers in Neuroscience.  Read Article

Neurocognitive Difficulties Among Youth with POTS within an Intensive Pain Rehabilitation Program. 2019. Journal of Pediatric Psychology.  Read Article

Cardiovagal modulation in pediatric functional gastrointestinal disorders. 2019. Neurogastroenterology & Motility.   Read Article

Dysautonomia and Headache in the Pediatric Population. 2019. Headache.  Read Article

Efficacy of β-Blockers on Postural Tachycardia Syndrome in Children and Adolescents: A Systematic Review and Meta-Analysis. 2019. Frontiers in Pediatrics.  Read Article

Utility of Diagnostic Studies for Upper Gastrointestinal Symptoms in Children with Orthostatic Intolerance. 2019. The Journal of Pediatrics.  Read Article

Neurological Symptoms of Vitamin B12 Deficiency: Analysis of Pediatric Patients. 2019. Acta Clinica Croatica.  Read Article

Postural Orthostatic Tachycardia Syndrome (POTS): A Case Report. 2019. Central European Journal of Paedatrics.  Read Article

Heart Rate Variability Predicts Therapeutic Response to Metoprolol in Children With Postural Tachycardia Syndrome. 2019. Frontiers in Neuroscience.  Read Article

Pain Management in Pediatric Patients with Postural Orthostatic Tachycardia Syndrome: Current Insights. 2019. Journal of Pain Research.  Read Article

Mechanisms of Tilt-Induced Vasovagal Syncope in Healthy Volunteers and Postural Tachycardia Syndrome Patients without Past History of Syncope. 2019. Physiological Reports.   Read Article

Orthostatic Heart Rate Does Not Predict Symptomatic Burden in Pediatric Patients with Chronic Orthostatic Intolerance. 2019. Journal of Gastroenterology.  Read Article

Clinical Course of Transgender Adolescents with Complicated Postural Orthostatic Tachycardia Syndrome Undergoing Hormonal Therapy in Gender Transition: A Case Series. 2019. Transgender Health.  Read Article

Frequency Domain Indices of Heart Rate Variability are Useful for Differentiating Vasovagal Syncope and Postural Tachycardia Syndrome in Children. 2019. The Journal of Pediatrics.  Read Article

Youth with Chronic Pain and Postural Orthostatic Tachycardia Syndrome (POTS): Treatment Mediators of Improvement in Functional Disability. 2018. Journal of Clinical Psychology in Medical Settings. Read Article

Demographics of a Large Paediatric Postural Orthostatic Tachycardia Syndrome Program. 2018. Cardiology in the Young.  Read Article

Increased Endogenous Sulfur Dioxide Involved in the Pathogenesis of Postural Tachycardia Syndrome in Children: A Case-Control Study. 2018. Chinese Medical Journal.  Read Article

Plasma Homocysteine Level in Children With Postural Tachycardia Syndrome. 2018. Frontiers in Pediatrics.  Read Article

Postural orthostatic tachycardia syndrome in children and adolescents. 2018. Autonomic Neuroscience: Basic and Clinical.  Read Article

Postural Orthostatic Tachycardia Syndrome in Young Diabetics. 2018. Galician Medical Journal.  Read Article

Value of immediate heart rate alteration from supine to upright in differential diagnosis between vasovagal syncope and postural tachycardia syndrome in children. 2018. Frontiers in Pediatrics.  Read Article

Etiologies and Management of Postural Tachycardia Syndrome in Children. 2018. The Egyptian Journal of Hospital Medicine.  Read Article

Pediatric Disorders of Orthostatic Intolerance. 2018. Pediatrics.  Read Article

Autoimmunity, Autonomic Neuropathy, and the HPV Vaccination: A Vulnerable Subpopulation. 2018. Clinical Pediatrics.  Read Article

Short-Term Outcome in Children and Adolescents with Orthostatic Intolerance and Postural Tachycardia Syndrome. 2018. Neurology.  Read Article

 Recent advances in the understanding of the mechanisms underlying postural tachycardia syndrome in children: practical implications for treatment. 2017. Cardiology in the Young. Read Article

Aquatic Therapy for a Patient with Postural Orthostatic Tachycardia Syndrome: a Case Report. 2017. Internet Journal of Allied Health Sciences and Practice. Read Article

A Case Report and Review of Postural Orthostatic Syndrome in an Adolescent. 2017. Journal of Pediatric Health Care.  Read Article

Incidence rates of Guillain Barré (GBS), chronic fatigue/systemic exertion intolerance disease (CFS/SEID) and postural orthostatic tachycardia syndrome (POTS) prior to introduction of human papilloma virus (HPV) vaccination among adolescent girls in Finland. 2017. ELSEVIER. Read Article

Reports of Postural Orthostatic Tachycardia Syndrome After Human Papillomavirus Vaccination in the Vaccine Adverse Event Reporting System. 2017. Journal of Adolescent Health.  Read Article

Salivary Cortisol Levels Predict Therapeutic Response to a Sleep- Promoting Method in Children with Postural Tachycardia Syndrome. 2017. The Journal of Pediatrics.  Read Article

Hemocytometric Measures Predict the Efficacy of Oral Rehydration for Children with Postural Tachycardia Syndrome. 2017. The Journal of Pediatrics.  Read Article

Serum Resistin Negatively Correlates with Clinical Severity of Postural Tachycardia Syndrome in Children. 2017. Pediatric Cardiology. Read Article

Pain is a Prevalent Symptom of Adolescents at Diagnosis with Postural Orthostatic Tachycardia Syndrome. 2017. Open Journal of Pain Medicine. Read Article

Cardiac Responses to Exercise Distinguish Postural Tachycardia Syndrome Variants. 2016. Physiological Reports.  Read Article

Baroflex Sensitivity Predicts Short-Term Outcome of Postural Tachycardia Syndrome in Children. 2016. Plos One. Read Article

Pathogenesis and Individualized Treatment for Postural Tachycardia Syndrome in Children. 2016. Chinese Medical Journal.  Read Article

Use of an Allostatic Neurotechnology by Adolescents with Postural Orthostatic Tachycardia Syndrome (POTS) is associated with Improvements in Heart Rate Variability and Changes in Temporal Lobe Electrical Activity. 2016. Experimental Brain Research.  Read Article

Interdisciplinary Treatment of Maladaptive Behaviors Associated with Postural Orthostatic Tachycardia Syndrome (POTS): A Case Report. 2015. Journal of Clinical Psychology in Medical Settings. Read Article

Syncope in Children and Adolescents. 2015. Adolscent Medicine.  Read Article

Complex Regional Pain Syndrome and Dysautonomia in a 14-Year-Old Girl Responsive to Therapeutic Plasma Exchange. 2015. Journal of Clinical Apheresis. Read Article

Plasma C-Type Natriuretic Peptide as a Predictor for Therapeutic Response to Metoprolol in Children with Postural Tachycardia Syndrome. 2015. Plos One.  Read Article

Cognitive dysfunction in postural tachycardia syndrome. 2015. Clinical Science (London). Read Article

A cross-sectional study on upright heart rate and BP changing characteristics: basic data for establishing diagnosis of postural orthostatic tachycardia syndrome and orthostatic hypertension. 2015. British Medical Journal.  Read Article

Suspected side effects to the quadrivalent human papilloma vaccine. 2015. Danish Medical Journal.  Read Article

Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. 2015. Experimental Brain Research.  Read Article

Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective. 2014. British Medical Journal Open.  Read Article

Postural Orthostatic Tachycardia Syndrome (POTS) and Vitamin B12 Deficiency in Adolescents. 2014. Pediatrics.  Read Article

High flow variant postural orthostatic tachycardia syndrome amplifies the cardiac output response to exercise in adolescents. 2014. Physiological Reports.  Read Article

Risk Factors for Postural Tachycardia Syndrome in Children and Adolescents. 2014. PLOS ONE.  Read Article

Peripheral Sympathetic Nerve Dysfunction in Adolescent Japanese Girls Following Immunization with the Human Papillomavirus Vaccine. 2014. Internal Medicine.  Read Article

Orthostatic plasma norepinephrine level as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome. 2014. Journal of Translational Medicine.  Read Article

Postural Orthostatic Tachycardia Syndrome (POTS) and Vitamin B12 Deficiency in Adolescents. 2014. Pediatrics.  Read Article

Chest Pain and Syncope in Children: A Practical Approach to the Diagnosis of Cardiac Disease. 2014. Journal of Pediatrics.  Read Article

A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome. 2014. Clinical Science.  Read Article

Higher postural heart rate increments on head-up tilt correlate with younger age but not orthostatic symptoms. 2013. Journal of Applied Physiology.  Read Article

Low iron storage in children with tilt positive neurally mediated syncope. 2013. World Journal of Pediatrics. Read Article

Orthostatic symptoms does not always manifest during tilt-table test in pediatric postural orthostatic tachycardia syndrome patient. 2013. Korean Journal of Pediatrics.  Read Article

What is brain fog? An evaluation of the symptom in postural tachycardia syndrome. 2013. Clinical Autonomic Research. Read Article

Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome. 2013. Frontiers in Physiology. Read Article

Common Syndromes of Orthostatic Intolerance. 2013. Pediatrics.  Read Article

Evidence of Small-Fiber Polyneuropathy in Unexplained, Juvenile-Onset, Widespread Pain Syndromes. 2013. Pediatrics.   Read Article

Midregional Pro-Adrenomedullin as a Predictor for Therapeutic Response to Midodrine Hydrochloride in Children With Postural Orthostatic Tachycardia Syndrome. 2012. Journal of the American College of Cardiology.  Read Article

Postural neurocognitive and neuronal activated cerebral blood flow deficits in young chronic fatigue syndrome patients with postural tachycardia syndrome. 2012. American Journal of Physiology.  Read Article

Gastric Electrical Activity Becomes Abnormal in the Upright Position in Patients With Postural Tachycardia Syndrome. 2010. Journal of Pediatric Gastroenterology & Nutrition.  Read Article

Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome. 2009. American Journal of Physiology - Heart and Circulatory Physiology.  Read Article

Postural Tachycardia Syndrome and Reflex Syncope: Similarities and Differences. 2009. Journal of Pediatrics.  Read Article

A Matched Case Control Study of Orthostatic Intolerance in Children/Adolescents With Chronic Fatigue Syndrome. 2008. Pediatric Research.  Read Article

Orthostatic Intolerance and Gastrointestinal Motility in Adolescents With Nausea and Abdominal Pain. 2008. Journal of Pediatric Gastroenterology & Nutrition.  Read Article

Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome. 2006. American Journal of Physiology - Heart and Circulatory Physiology.  Read Article

Pediatric Autonomic Disorders. 2006. Pediatrics.  Read Article

Postural hypocapnic hyperventilation is associated with enhanced peripheral vasoconstriction in postural tachycardia syndrome with normal supine blood flow. 2006. American Journal of Physiology - Heart and Circulatory Physiology.   Read Article

Splanchnic hyperemia and hypervolemia during Valsalva maneuver in postural tachycardia syndrome. 2005. American Journal of Physiology - Heart and Circulatory Physiology. Read Article

Decreased Microvascular Nitric Oxide–Dependent Vasodilation in Postural Tachycardia Syndrome. 2005. Circulation.  Read Article

Relation of Postural Vasovagal Syncope to Splanchnic Hypervolemia in Adolescents. 2004. Circulation.  Read Article

Reflex syncope in children and adolescents. 2004. Heart.  Read Article

Syncope in childhood. 2003. Archives of Disease in Childhood.  Read Article

Microvascular Filtration Is Increased in Postural Tachycardia Syndrome. 2002. Circulation.  Read Article

Clinical and Physiological Effects of an Acute α-1 Adrenergic Agonist and a β-1 Adrenergic Antagonist in Chronic Orthostatic Intolerance. 2002. Circulation.  Read Article

Pooling in Chronic Orthostatic Intolerance: Arterial Vasoconstrictive but not Venous Compliance Defects. 2002. Circulation.  Read Article

Orthostasis fails to produce active limb venoconstriction in adolescents. 2001. Journal of Applied Physiology.  Read Article

Autonomic Abnormalities in Children With Functional Abdominal Pain: Coincidence or Etiology? 2001. Journal of Pediatric Gastroenterology & Nutrition.   Read Article

Reflex vascular defects in the orthostatic tachycardia syndrome of adolescents. 2001. Journal of Applied Physiology.  Read Article

Autoantibodies to Ganglionic Acetylcholine Receptors in Autoimmune Autonomic Neuropathies. 2000. New England Journal of Medicine.  Read Article

Autonomic Nervous System Dysfunction in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Fatigue Syndrome Is Characterized by Attenuated Vagal Baroreflex and Potentiated Sympathetic Vasomotion. 2000. Pediatric Research.  Read Article

Vascular perturbations in the chronic orthostatic intolerance of the postural orthostatic tachycardia syndrome. 2000. Journal of Applied Physiology.  Read Article